Enfermedad de Parkinson, información, noticias, tratamientos, fármacos, investigación, terapias.

Science Daily

Information on Parkinson's disease. Learn about Parkinson's disease treatments, symptoms, new research and medication.
  1. Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal development, structure, and function, but, this study offers a clear demonstration that they also keep dopamine cells alive.
  2. Newly discovered gene mutations may help explain the cause of a disease that drastically impairs walking and thinking.
  3. The most common gene mutation associated with Parkinson's alters cells circulating outside the brain, not within, offering a new understanding of what causes the disease.
  4. Working with lab-grown human brain cells, researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson's disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease.
  5. Researchers investigate the connection between misfolded proteins and the destruction of mitochondria in neurons.
  6. A genetics research team has solved a dilemma facing researchers who use genomewide association studies (GWAS) by developing a new approach that strategically 'filters' which genes are worth further study. The researchers hope this strategy will accelerate the study of diseases such as Parkinson's, Alzheimer's, schizophrenia and even addiction by helping researchers avoid 'dead-end paths.' They are optimistic that this strategy will gain widespread use and will save researchers time and money.
  7. If the sense of smell disappears, this can indicate a disease such as Alzheimer's or Parkinson's disease. However, unlike previously assumed, general degenerations in the nervous system do not play a leading role in the loss of the sense of smell with increasing age, but individual nerve cells or classes of nerves are decisive.
  8. Levels of a protein found in the brain called alpha-synuclein are significantly lower than normal in cerebrospinal fluid collected in Parkinson's disease patients suffering from postural instability and gait difficulty, a study has found.
  9. Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease.
  10. With the aid of a PET camera, researchers have developed a new method for investigating the dopamine system in the brains of patients suffering from Parkinson’s disease. The method measures levels of a protein called dopamine transporter and could lead to improved diagnosis of Parkinson’s disease and the development of new treatments.

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