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A Critical Evaluation of the Ubiquitin-Proteasome System in Parkinson's Disease

Short Description:
The evidence for impairment in the ubiquitin proteasome system (UPS) in Parkinson Disease (PD) is mounting and becoming increasingly more convinc...
Submitted On:
27 Feb 2010
File Size:
169.89 Kb
Downloads:
3
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Total Votes:0
File Author:
Casey Cook and Leonard Petrucelli

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

Short Description:
More than 80 years after iron accumulation was initially described in the substantia nigra (SN) of Parkinson's disease (PD) patients, the mechanism...
Submitted On:
30 Nov 2009
File Size:
824.44 Kb
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0
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Activation of Retinoid X Receptor increases dopamine cell survival in models for Parkinson's disease

Short Description:
We studied the potential neurotrophic effects of the RXR ligand LG100268 (LG268) and the RXR-Nurr1 ligand XCT0139508 (XCT) in neuronal cultures der...
Submitted On:
31 Dec 2009
File Size:
302.66 Kb
Downloads:
1
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Total Votes:0
File Author:
Stina Friling, Maria Bergsland, and Susanna Kjellander

Adult neurogenesis neuroinflammation and therapeutic potential adult neural stem cells

Submitted On:
14 Nov 2008
File Size:
111.4 KB
Downloads:
4
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Total Votes:0
File Author:
AdminUCP

Agonism_of_Peroxisome_Neuroinflamation_PD.pdf

Submitted On:
08 Nov 2008
File Size:
220.6 KB
Downloads:
2
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Total Votes:0
File Author:
AdminUCP

ALPHA-SYNUCLEIN-IMMUNOPOSITIVE MYENTERIC NEURONS AND VAGAL PREGANGLIONIC TERMINALS: AUTONOMIC PATHWAY IMPLICATED IN PARKINSON’S DISEASE?

Short Description:
The protein alpha-synuclein is implicated in the development of Parkinson’s disease. The molecule forms Lewy body aggregates that are hallmarks o...
Submitted On:
16 May 2009
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0
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File Author:
Robert J. Phillips, Gary C. Walter, Sarah L. Wilder, Elizabeth A. Baronowsky, and Terry L. Powley

Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by L-DOPA treatment

Short Description:
Dysregulation of dopamine (DA) receptors is believed to underlie Parkinson’s disease pathology and L-DOPA-induced motor complications. DA recepto...
Submitted On:
25 Mar 2009
Downloads:
0
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Antioxidants in Central Nervous System Diseases

Short Description:
Oxidative damage is strongly implicated in the pathogenesis of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral scle...
Submitted On:
18 Apr 2009
File Size:
368.03 Kb
Downloads:
1
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Total Votes:1

Autologous transplants of Adipose-Derived Adult Stromal (ADAS) afford dopaminergic neuroprotection in a model of Parkinson’s disease

Short Description:
Adult adipose contains stromal progenitor cells with neurogenic potential. However, the stability of neuronal phenotypes adopted by Adipose-Derived...
Submitted On:
03 Mar 2009
File Size:
737.10 Kb
Downloads:
0
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Total Votes:0

A_protective_role_for_autophagy.pdf

Submitted On:
08 Nov 2008
File Size:
276.7 KB
Downloads:
3
Rating:
Total Votes:0
File Author:
AdminUCP
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