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Impaired verbal memory in Parkinson disease: relationship to prefrontal dysfunction and somatosensory discrimination
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- Description:
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To study the neurocognitive profile and its relationship to prefrontal dysfunction in non-demented Parkinson's disease (PD) with deficient haptic perception.Methods:Twelve right-handed patients with PD and 12 healthy control subjects underwent thorough neuropsychological testing including Rey complex figure, Rey auditory verbal and figural learning test, figural and verbal fluency, and Stroop test. Test scores reflecting significant differences between patients and healthy subjects were correlated with the individual expression coefficients of one principal component, obtained in a principal component analysis of an oxygen-15-labeled water PET study exploring somatosensory discrimination that differentiated between the two groups and involved prefrontal cortices.
- Submitted On:
- 13 Jan 2010
- File Size:
- 192.11 Kb
- Downloads:
- 2
- File Author:
- Stephan Bohlhalter, Eugenio Abela, Dorothea Weniger, and Bruno Weder
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